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For adults with Familial Chylomicronemia Syndrome (FCS),

Reach a new

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Take the path forward with a reduction in triglycerides

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For adults with Familial Chylomicronemia Syndrome (FCS),

All the placesyou will

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Designed to help lower triglycerides in adults with FCS

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For adults with Familial Chylomicronemia Syndrome (FCS),

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Patients saw an 80% median reduction in triglycerides from baseline at Month 10

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For adults with Familial Chylomicronemia Syndrome (FCS),

On your mark,GET SET,

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Take the dive into how Redemplo® reduces triglycerides

Now Approved Redemplo (plozasiran) injection

Redemplo® is a treatment for adults with FCS that works in combination with diet to reduce triglycerides

Data showed patients taking Redemplo saw a significant reduction in triglycerides, and a lowered number of acute pancreatitis attacks, with just one dose every 3 months.*

80% Reduction in Triglycerides

A significant reduction of 80% in triglycerides from baseline was seen at 10 months

Explore the results

Lowered Number of Acute Pancreatitis Attacks*

Fewer people had acute pancreatitis attacks: 2 (8%) compared with 5 (20%) on placebo

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Convenient Dosing Schedule

The only FCS injection that is just one dose every 3 months

Uncover the dosing schedule

*The clinical study included an evaluation of acute pancreatitis events that occurred in patients taking Redemplo compared to those taking placebo. Redemplo has not been proven to reduce acute pancreatitis events.

Redemplo 25 mg reduced median triglycerides by 80% (from 2008 mg/dL to 443 mg/dL) compared with 17% for placebo (from 2053 mg/dL to 1614 mg/dL).

With the Rely On Redemplo® Patient Support Program, get support throughout your treatment journey

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Do you know the risks of extremely high triglycerides?

Learn more about FCS

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Steep reductions in
triglycerides

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Indication & Important Safety Information

Indication

REDEMPLO® (plozasiran) is an injectable prescription medicine used together with a low-fat diet to reduce triglycerides (fat in the blood) in adults with a condition that keeps the body from breaking down fats called familial chylomicronemia syndrome (FCS).

Important Safety Information

Before you start using REDEMPLO, tell your healthcare provider about all your medical conditions, including if you are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. It is not known if REDEMPLO could harm your unborn baby, or if it passes into your breast milk and could harm your breastfeeding baby.

Tell your healthcare provider or pharmacist about any prescription and over-the-counter medicines, vitamins, or herbal supplements you take.

What are the possible side effects of REDEMPLO?

The most common side effects of REDEMPLO include increased blood sugar levels, headache, nausea, and injection site reactions (pain, redness, or swelling).

These are not all the possible side effects of REDEMPLO. Tell your healthcare provider or treatment team if you have any side effect that bothers you or that does not go away.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/safety/medwatch , or call 1-800-FDA-1088.

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