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Safety

Like all medications, Redemplo® (plozasiran) can cause side effects

Here is a summary of the most common side effects experienced in the clinical study:

INCREASE IN BLOOD SUGAR (HYPERGLYCEMIA)

of patients experienced an increase in their blood sugar (hyperglycemia) while using Redemplo.

QUESTIONS TO ASK YOUR DOCTOR
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  • How will we keep track of any changes in my diabetes while I’m on Redemplo?
  • Will I need extra blood sugar checks during treatment?
  • What should I do if my blood sugar readings are higher than usual?
  • If my blood sugar readings change, how will my treatment plan be adjusted?

Headache

of patients experienced headache while using Redemplo.

QUESTIONS TO ASK YOUR DOCTOR
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  • What if I'm concerned a headache may be related to my treatment?
  • Do these symptoms usually go away on their own?

Nausea

of patients experienced nausea while using Redemplo.

QUESTIONS TO ASK YOUR DOCTOR
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  • If I feel nauseous, what can I do to help reduce symptoms?
  • Does nausea usually go away on its own?

Injection site reactions

of patients experienced injection site reactions while using Redemplo.

QUESTIONS TO ASK YOUR DOCTOR
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  • Would rotating injection sites help reduce reactions?
  • Is there anything I can do before or after an injection to minimize reactions?

Tell your healthcare provider if you experience any of the above side effects. These are not all of the possible side effects of Redemplo

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Convenient dosing with one injection every 3 months

Explore convenient dosing

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Steep reductions in triglycerides

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Indication & Important Safety Information

Indication

REDEMPLO® (plozasiran) is an injectable prescription medicine used together with a low-fat diet to reduce triglycerides (fat in the blood) in adults with a condition that keeps the body from breaking down fats called familial chylomicronemia syndrome (FCS).

Important Safety Information

Before you start using REDEMPLO, tell your healthcare provider about all your medical conditions, including if you are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. It is not known if REDEMPLO could harm your unborn baby, or if it passes into your breast milk and could harm your breastfeeding baby.

Tell your healthcare provider or pharmacist about any prescription and over-the-counter medicines, vitamins, or herbal supplements you take.

What are the possible side effects of REDEMPLO?

The most common side effects of REDEMPLO include increased blood sugar levels, headache, nausea, and injection site reactions (pain, redness, or swelling).

These are not all the possible side effects of REDEMPLO. Tell your healthcare provider or treatment team if you have any side effect that bothers you or that does not go away.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/safety/medwatch , or call 1-800-FDA-1088.

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